Erik Siegrist previews the Monday night game as Jimmy Garoppolo and the 49ers face the division-rival Cardinals in Mexico City.
As perhaps the AFC North's most complete team, the Colts boast the reigning rushing champ in Jonathan Taylor behind a top-10 offensive line. Beyond Taylor, Michael Pittman represents the biggest fantasy asset.
In the wake of Philip Rivers' retirement, the Colts have decided to give Carson Wentz a second chance. But Indy's offense nonetheless revolves around second-year running back Jonathan Taylor.
After previously spending his NFL career as a pass-rushing DE/OLB tweener, Collins has mostly shed the pass-rushing reps in Detroit and is piling up tackles instead.